ARCIMBOLDO

ARCIMBOLDO: Crystallographic Ab Initio protein solution below atomic resolution

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Ab Initio macromolecular phasing has been traditionally limited to small proteins at atomic resolution (1.2Å or better unless heavy atoms are present). ARCIMBOLDO constitutes a general method for 2Å data, based on combination of location of model fragments like small α-helices with PHASER and density modification with SHELXE, distributed over a grid of computers.

Here you can find a general description of the ARCIMBOLDO programs.

ARCIMBOLDO is within CCP4 since January 2016.

arcimboldo
ARCIMBOLDO: Crystallographic Ab Initio protein solution below atomic resolution Dayte D. Rodríguez Martínez, Christian Grosse, Sebastian Himmel, César González, Iñaki M. de Ilarduya, Stefan Becker, George M. Sheldrick and Isabel Usón.

Nature Methods 6(9): 651-653 (2009) (doi:10.1038/nmeth.1365)