ARCIMBOLDO

ARCIMBOLDO: Crystallographic Ab Initio protein solution below atomic resolution

ARCIMBOLDO has joined CCP4 on January 2016.

More on ARCIMBOLDO_LITE here.

Ab Initio macromolecular phasing has been traditionally limited to small proteins at atomic resolution (1.2Å or better unless heavy atoms are present). ARCIMBOLDO constitutes a general method for 2Å data, based on combination of location of model fragments like small α-helices with PHASER and density modification with SHELXE, distributed over a grid of computers.

Here you can find a general description of the ARCIMBOLDO programs.

arcimboldo
ARCIMBOLDO: Crystallographic Ab Initio protein solution below atomic resolution Dayte D. Rodríguez Martínez, Christian Grosse, Sebastian Himmel, César González, IƱaki M. de Ilarduya, Stefan Becker, George M. Sheldrick and Isabel Usón.

Nature Methods 6(9): 651-653 (2009) (doi:10.1038/nmeth.1365)